5-Bromo-N-(3,4-dimethoxybenzyl)pyridin-2-amine
نویسندگان
چکیده
The title compound, C(14)H(15)BrN(2)O(2), an inter-mediate in drug discovery, was synthesized by the reaction of 5-bromo-pyridin-2-amine and 3,4-dimeth-oxy-benzaldehyde. In the crystal, molecules are linked via pairs ofN-H⋯N hydrogen bonds, leading to the formation of inversion dimers. A short contact occurs between the aryl H atom (ortho position from N) and the centroid of the benzene ring.
منابع مشابه
6-Bromo-N-(6-bromopyridin-2-yl)-N-[4-(2,3-dihydrothieno[3,4-b][1,4]dioxin-5-yl)phenyl]pyridin-2-amine
In the title mol-ecule, C22H15Br2N3O2S, the central benzene ring forms dihedral angles of 12.39 (17), 56.66 (17) and 74.71 (19)°, respectively, with the mean planes of the thio-phene and two pyridine rings. The dioxane ring is in a half-chair conformation. An intra-molecular C-H⋯O hydrogen forms an S(6) ring. The amine N atom is sp (2)-hybridized.
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